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ELK Biotechnology

SKU:ES9593

DPOG1 Rabbit Polyclonal Antibody

DPOG1 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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DPOG1 Rabbit Polyclonal Antibody

Overview

Product name: DPOG1 rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 136kD
GeneID(Human): 5428
Human Swiss-Prot No: P54098
Cellular localization: Mitochondrion . Mitochondrion matrix, mitochondrion nucleoid .
Background: Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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