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ELK Biotechnology

SKU:ES9581

DOC11 Rabbit Polyclonal Antibody

DOC11 Rabbit Polyclonal Antibody

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DOC11 Rabbit Polyclonal Antibody

Overview

Product name: DOC11 rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 228kD
GeneID(Human): 139818
Human Swiss-Prot No: Q5JSL3
Cellular localization: intracellular,cytosol,
Background: domain:The DHR-2 domain is necessary for the GEF activity.,function:Guanine nucleotide-exchange factor (GEF) that activates CDC42 by exchanging bound GDP for free GTP.,miscellaneous:'Zizim' means 'spike' in Hebrew.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the DOCK family.,similarity:Contains 1 DHR-1 (CZH-1) domain.,similarity:Contains 1 DHR-2 (CZH-2) domain.,similarity:Contains 1 PH domain.,subunit:Interacts with CDC42.,
Species Reactivity: Human;Mouse
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