CHD8 Rabbit Polyclonal Antibody

Name: CHD8 Rabbit Polyclonal Antibody
Brand: ELK Biotechnology
SKU: ES9540
Price: 248.0 USD
Availability: InStock

$248.00 USD

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Size 100ul

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CHD8 Rabbit Polyclonal Antibody

Product name:	CHD8 rabbit pAb
Applications:	IHC;IF
Recommended Dilutions:	IHC-p 1:50-300
Immunogen:	Synthesized peptide derived from part region of human protein
Storage:	Rabbit
Storage:	-20°C/1 year
Clonality:	Polyclonal
Isotype:	IgG
Concentration:	1 mg/ml
Observed Band:	283kD
GeneID（Human）:	57680
Human Swiss-Prot No:	Q9HCK8
Cellular localization:	Nucleus . Localizes to the promoter regions of several CTNNB1-responsive genes. Also present at known CTCF target sites. .
Background:	This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010],
Species Reactivity:	Human;Rat;Mouse;

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