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ELK Biotechnology
SKU:ES9509
CTND2 Rabbit Polyclonal Antibody
CTND2 Rabbit Polyclonal Antibody
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$248.00 USD
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CTND2 Rabbit Polyclonal Antibody
Overview
| Product name: | CTND2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 134kD |
| GeneID（Human）: | 1501 |
| Human Swiss-Prot No: | Q9UQB3 |
| Cellular localization: | Nucleus . Cell junction, adherens junction . Cell projection, dendrite . Perikaryon . |
| Background: | catenin delta 2(CTNND2) Homo sapiens This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013], |
| Species Reactivity: | Human;Mouse |
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