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ELK Biotechnology

SKU:ES9467

PDE1B Rabbit Polyclonal Antibody

PDE1B Rabbit Polyclonal Antibody

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PDE1B Rabbit Polyclonal Antibody

Overview

Product name: PDE1B rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from part region of human protein
Storage: -20°C/1 year
Storage: Rabbit
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 58kD
GeneID(Human): 5153
Human Swiss-Prot No: Q01064
Cellular localization: Cytoplasm, cytosol .
Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011],
Species Reactivity: Human;Rat;Mouse;
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