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ELK Biotechnology
SKU:ES9466
PDE1A Rabbit Polyclonal Antibody
PDE1A Rabbit Polyclonal Antibody
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$248.00 USD
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PDE1A Rabbit Polyclonal Antibody
Overview
| Product name: | PDE1A rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 58kD |
| GeneID（Human）: | 5136 |
| Human Swiss-Prot No: | P54750 |
| Cellular localization: | nucleus,cytosol,neuronal cell body, |
| Background: | Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009], |
| Species Reactivity: | Human;Mouse |
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