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ELK Biotechnology
SKU:ES9429
ABCCB Rabbit Polyclonal Antibody
ABCCB Rabbit Polyclonal Antibody
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$248.00 USD
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ABCCB Rabbit Polyclonal Antibody
Overview
| Product name: | ABCCB rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 50-130 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 152kD |
| GeneID（Human）: | 85320 |
| Human Swiss-Prot No: | Q96J66 |
| Cellular localization: | Cell membrane ; Multi-pass membrane protein . Vacuole membrane . Cytoplasmic vesicle membrane . Apical cell membrane ; Multi-pass membrane protein. |
| Background: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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