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ELK Biotechnology
SKU:ES9424
ABCD2 Rabbit Polyclonal Antibody
ABCD2 Rabbit Polyclonal Antibody
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$248.00 USD
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ABCD2 Rabbit Polyclonal Antibody
Overview
| Product name: | ABCD2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 310-390 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 81kD |
| GeneID（Human）: | 225 |
| Human Swiss-Prot No: | Q9UBJ2 |
| Cellular localization: | Peroxisome membrane ; Multi-pass membrane protein . |
| Background: | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe |
| Species Reactivity: | Human;Rat;Mouse; |
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