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ELK Biotechnology
SKU:ES9362
ATS4 Rabbit Polyclonal Antibody
ATS4 Rabbit Polyclonal Antibody
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$248.00 USD
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ATS4 Rabbit Polyclonal Antibody
Overview
| Product name: | ATS4 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 240-320 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 92kD |
| GeneID（Human）: | 9507 |
| Human Swiss-Prot No: | O75173 |
| Cellular localization: | Secreted, extracellular space, extracellular matrix . |
| Background: | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The expression of this gene is upregulated in arthritic disease and this may contribute to disease progression through the degradatio |
| Species Reactivity: | Human;Mouse;Rat |
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