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ELK Biotechnology
SKU:ES9341
AVR2B Rabbit Polyclonal Antibody
AVR2B Rabbit Polyclonal Antibody
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$248.00 USD
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AVR2B Rabbit Polyclonal Antibody
Overview
| Product name: | AVR2B rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 40-120 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 56kD |
| GeneID（Human）: | 93 |
| Human Swiss-Prot No: | Q13705 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . |
| Background: | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. Th |
| Species Reactivity: | Human;Mouse;Rat |
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