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ELK Biotechnology
SKU:ES9271
ERCC2 Rabbit Polyclonal Antibody
ERCC2 Rabbit Polyclonal Antibody
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$248.00 USD
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ERCC2 Rabbit Polyclonal Antibody
Overview
| Product name: | ERCC2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 220-300 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 83kD |
| GeneID（Human）: | 2068 |
| Human Swiss-Prot No: | P18074 |
| Cellular localization: | Nucleus . Cytoplasm, cytoskeleton, spindle . |
| Background: | The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008], |
| Species Reactivity: | Human;Mouse |
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