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ELK Biotechnology

SKU:ES9222

PLCD1 Rabbit Polyclonal Antibody

PLCD1 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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PLCD1 Rabbit Polyclonal Antibody

Overview

Product name: PLCD1 rabbit pAb
Applications: WB;ELISA
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 90-170
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 83kD
GeneID(Human): 5333
Human Swiss-Prot No: P51178
Cellular localization: intracellular,cytoplasm,cytosol,plasma membrane,extracellular exosome,
Background: This gene encodes a member of the phospholipase C family. Phospholipase C isozymes play critical roles in intracellular signal transduction by catalyzing the hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers diacylglycerol (DAG) and inositol triphosphate (IP3). The encoded protein functions as a tumor suppressor in several types of cancer, and mutations in this gene are a cause of hereditary leukonychia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011],
Species Reactivity: Human;Mouse;Rat
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