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ELK Biotechnology
SKU:ES9135
CRY1 Rabbit Polyclonal Antibody
CRY1 Rabbit Polyclonal Antibody
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$248.00 USD
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CRY1 Rabbit Polyclonal Antibody
Overview
| Product name: | CRY1 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 120-200 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 64kD |
| GeneID（Human）: | 1407 |
| Human Swiss-Prot No: | Q16526 |
| Cellular localization: | Cytoplasm. Nucleus . Translocated to the nucleus through interaction with other clock proteins such as PER2 or ARNTL/BMAL1. . |
| Background: | This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014], |
| Species Reactivity: | Human;Mouse;Rat |
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