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ELK Biotechnology
SKU:ES9124
COX2 Rabbit Polyclonal Antibody
COX2 Rabbit Polyclonal Antibody
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$248.00 USD
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COX2 Rabbit Polyclonal Antibody
Overview
| Product name: | COX2 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 40-120 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 24kD |
| GeneID（Human）: | 4513 |
| Human Swiss-Prot No: | P00403 |
| Cellular localization: | Mitochondrion inner membrane ; Multi-pass membrane protein . |
| Background: | cofactor:Copper A.,disease:Defects in MT-CO2 are a cause of cytochrome c oxidase deficiency (COX deficiency) [MIM:220110]; also called mitochondrial complex IV deficiency. COX deficiency is a clinically heterogeneous disorder. The clinical features are ranging from isolated myopathy to severe multisystem disease, with onset from infancy to adulthood.,disease:Defects in MT-CO2 are associated with tumor formation.,function:Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.,similarity:Belongs to the cytochrome c oxidase subunit 2 family., |
| Species Reactivity: | Human;Rat;Mouse; |
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