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ELK Biotechnology

SKU:ES9000

BCL3 Rabbit Polyclonal Antibody

BCL3 Rabbit Polyclonal Antibody

Regular price $248.00 USD
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BCL3 Rabbit Polyclonal Antibody

Overview

Product name: BCL3 rabbit pAb
Applications: IHC;IF;WB
Recommended Dilutions: WB 1:500-2000 ELISA 1:5000-20000
Immunogen: Synthesized peptide derived from human protein . at AA range: 340-420
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 49kD
GeneID(Human): 602
Human Swiss-Prot No: P20749
Cellular localization: Nucleus. Cytoplasm . Cytoplasm, perinuclear region . Ubiquitination via 'Lys-63'-linked ubiquitin chains is required for nuclear accumulation. .
Background: This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse;;Goat
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