Parafibromin (Cell division cycle protein 73 homolog) (Hyperparathyroidism 2 protein)
Applications:
WB;ELISA
Recommended Dilutions:
WB 1:500-2000, ELISA 1:10000-20000
Immunogen:
Synthesized peptide derived from human Parafibromin. at AA range: 51-100
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
60kD
GeneID（Human）:
79577
Human Swiss-Prot No:
Q6P1J9
Cellular localization:
Nucleus .
Background:
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma. [provided by RefSeq, Jul 2009],
