Granzyme M (EC 3.4.21.-;Met-1 serine protease;Hu-Met-1;Met-ase;Natural killer cell granular protease)
Applications:
IHC;IF;ELISA
Recommended Dilutions:
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen:
Synthetic peptide from human protein at AA range: 207-256
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
GeneID（Human）:
3004
Human Swiss-Prot No:
P51124
Cellular localization:
Secreted. Cytoplasmic granule. Granules of large granular lymphocytes.
Background:
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012],
