C-X-C chemokine receptor type 1 (CXC-R1;CXCR-1;CDw128a;High affinity interleukin-8 receptor A;IL-8R A;IL-8 receptor type 1;CD antigen CD181)
Applications:
WB;IHC;IF;ELISA
Recommended Dilutions:
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen:
Synthetic peptide from human protein at AA range: 1-50
Storage:
-20°C/1 year
Storage:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
GeneID（Human）:
3577
Human Swiss-Prot No:
P25024
Cellular localization:
Cell membrane; Multi-pass membrane protein.
Background:
C-X-C motif chemokine receptor 1(CXCR1) Homo sapiens The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008],
