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ELK Biotechnology
SKU:ES8779
Integrin αE Rabbit Polyclonal Antibody
Integrin αE Rabbit Polyclonal Antibody
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$248.00 USD
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Integrin αE Rabbit Polyclonal Antibody
Overview
| Product name: | Integrin αE rabbit pAb |
| Alternative Names: | Integrin alpha-E (HML-1 antigen;Integrin alpha-IEL;Mucosal lymphocyte 1 antigen;CD antigen CD103) [Cleaved into: Integrin alpha-E light chain; Integrin alpha-E heavy chain] |
| Applications: | WB;IHC;IF;ELISA |
| Recommended Dilutions: | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Immunogen: | Synthetic peptide from human protein at AA range: 710-770 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| GeneID(Human): | 3682 |
| Human Swiss-Prot No: | P38570 |
| Cellular localization: | Membrane; Single-pass type I membrane protein. |
| Background: | integrin subunit alpha E(ITGAE) Homo sapiens Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human;Rat;Mouse; |
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