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ELK Biotechnology

ES8774

Ob Rabbit Polyclonal Antibody

Ob Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Ob Rabbit Polyclonal Antibody

Overview

Product name: Ob rabbit pAb
Alternative Names: Leptin (Obese protein;Obesity factor)
Applications: IHC;IF;ELISA
Recommended Dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 10-50
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID（Human）: 3952
Human Swiss-Prot No: P41159
Cellular localization: Secreted .
Background: This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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