Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)
Applications:
IHC;IF;ELISA
Recommended Dilutions:
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen:
Synthetic peptide from human protein at AA range: 630-680
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
GeneID（Human）:
23368
Human Swiss-Prot No:
Q96KQ4
Cellular localization:
Cytoplasm . Nucleus . Predominantly cytoplasmic. Some fraction is nuclear.
Background:
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008],
