Ubiquitin-like-conjugating enzyme ATG10 (EC 6.3.2.-;Autophagy-related protein 10;APG10-like)
Applications:
IHC;IF;ELISA
Recommended Dilutions:
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen:
Synthetic peptide from human protein at AA range: 1-50
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
GeneID（Human）:
83734
Human Swiss-Prot No:
Q9H0Y0
Cellular localization:
Cytoplasm .
Background:
Autophagy is a process for the bulk degradation of cytosolic compartments by lysosomes. ATG10 is an E2-like enzyme involved in 2 ubiquitin-like modifications essential for autophagosome formation: ATG12 (MIM 609608)-ATG5 (MIM 604261) conjugation and modification of a soluble form of MAP-LC3 (MAP1LC3A; MIM 601242), a homolog of yeast Apg8, to a membrane-bound form (Nemoto et al., 2003 [PubMed 12890687]).[supplied by OMIM, Mar 2008],
