Glutathione S-transferase A1 (EC 2.5.1.18;GST HA subunit 1;GST class-alpha member 1;GST-epsilon;GSTA1-1;GTH1)
Applications:
WB;IP;IHC;IF;ELISA
Recommended Dilutions:
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen:
The antiserum was produced against synthesized peptide derived from the Internal region of human GSTA1. AA range:91-140
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
GeneID（Human）:
2938
Human Swiss-Prot No:
P08263
Cellular localization:
Cytoplasm.
Background:
This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
