Interleukin-18 receptor accessory protein (IL-18 receptor accessory protein;IL-18RAcP;Accessory protein-like;AcPL;CD218 antigen-like family member B;CDw218b;IL-1R accessory protein-like;IL-1RAcPL;Interleukin-1 receptor 7;IL-1R-7;IL-1R7;Interleukin-18 receptor accessory protein-like;Interleukin-18 receptor beta;IL-18R-beta;IL-18Rbeta;CD antigen CD218b)
Applications:
IHC;IF;ELISA
Recommended Dilutions:
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen:
Synthetic peptide from human protein at AA range: 291-340
Storage:
-20°C/1 year
Storage:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
GeneID（Human）:
8807
Human Swiss-Prot No:
O95256
Cellular localization:
Cell membrane ; Single-pass type I membrane protein .
Background:
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014],
