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ELK Biotechnology

ES8690

DDR2 Rabbit Polyclonal Antibody

DDR2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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DDR2 Rabbit Polyclonal Antibody

Overview

Product name: DDR2 rabbit pAb
Alternative Names: Discoidin domain-containing receptor 2 (Discoidin domain receptor 2) (EC 2.7.10.1) (CD167 antigen-like family member B) (Discoidin domain-containing receptor tyrosine kinase 2) (Neurotrophic tyrosine kinase, receptor-related 3) (Receptor protein-tyrosine kinase TKT) (Tyrosine-protein kinase TYRO10) (CD antigen CD167b)
Applications: IF;IHC;ELISA
Recommended Dilutions: IHC-p 1:50-200, IF1：500 ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 31-80
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID（Human）: 4921
Human Swiss-Prot No: Q16832
Cellular localization: Cell membrane ; Single-pass type I membrane protein .
Background: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcr
Species Reactivity: Human;Mouse
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