Semaphorin-7A (CDw108;JMH blood group antigen;John-Milton-Hargen human blood group Ag;Semaphorin-K1;Sema K1;Semaphorin-L;Sema L;CD antigen CD108)
Applications:
IHC;IF;ELISA
Recommended Dilutions:
IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen:
Synthetic peptide from human protein at AA range: 101-150
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
GeneID（Human）:
8482
Human Swiss-Prot No:
O75326
Cellular localization:
Cell membrane ; Lipid-anchor, GPI-anchor ; Extracellular side . Detected in a punctate pattern on the cell membrane of basal and supra-basal skin keratinocytes.
Background:
This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016],
