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ELK Biotechnology

ES8673

CD11b Rabbit Polyclonal Antibody

CD11b Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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CD11b Rabbit Polyclonal Antibody

Overview

Product name: CD11b rabbit pAb
Alternative Names: Integrin alpha-M (CD11 antigen-like family member B;CR-3 alpha chain;Cell surface glycoprotein MAC-1 subunit alpha;Leukocyte adhesion receptor MO1;Neutrophil adherence receptor;CD antigen CD11b)
Applications: IHC;IF;mult-IHC;ELISA
Recommended Dilutions: IHC-p 1:50-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 280-360
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
GeneID（Human）: 3684
Human Swiss-Prot No: P11215
Cellular localization: Cell membrane ; Single-pass type I membrane protein . Membrane raft ; Single-pass type I membrane protein .
Background: integrin subunit alpha M(ITGAM) Homo sapiens This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],
Species Reactivity: Human;Rat;Mouse;
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