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ELK Biotechnology
SKU:ES8663
OSM Rabbit Polyclonal Antibody
OSM Rabbit Polyclonal Antibody
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$248.00 USD
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OSM Rabbit Polyclonal Antibody
Overview
| Product name: | OSM rabbit pAb |
| Alternative Names: | Oncostatin-M (OSM) |
| Applications: | IHC;IF;ELISA |
| Recommended Dilutions: | IHC-p 1:50-200, ELISA 1:10000-20000 |
| Immunogen: | Synthetic peptide from human protein at AA range: 50-100 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| GeneID(Human): | 5008 |
| Human Swiss-Prot No: | P13725 |
| Cellular localization: | Secreted. |
| Background: | This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016], |
| Species Reactivity: | Human;Rat;Mouse; |
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Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:200 -
Immunohistochemical analysis of paraffin-embedded human-colon, antibody was diluted at 1:200 -
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200 -
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:200
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