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ELK Biotechnology

ES8660

Dsg1 Rabbit Polyclonal Antibody

Dsg1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Dsg1 Rabbit Polyclonal Antibody

Overview

Product name: Dsg1 rabbit pAb
Alternative Names: Desmoglein-1 (Cadherin family member 4;Desmosomal glycoprotein 1;DG1;DGI;Pemphigus foliaceus antigen)
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 30-90
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 160kD
GeneID（Human）: 1828
Human Swiss-Prot No: Q02413
Cellular localization: Cell membrane ; Single-pass type I membrane protein . Cell junction, desmosome.
Background: This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma. [provided by RefSeq, Feb 2015],
Species Reactivity: Human;Mouse;Rat
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