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ELK Biotechnology

ES8651

EGF Rabbit Polyclonal Antibody

EGF Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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EGF Rabbit Polyclonal Antibody

Overview

Product name: EGF rabbit pAb
Alternative Names: Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)]
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 1000-1060
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 130kD
GeneID（Human）: 1950
Human Swiss-Prot No: P01133
Cellular localization: Membrane; Single-pass type I membrane protein.
Background: This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],
Species Reactivity: Human;Rat;Mouse;
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