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ELK Biotechnology

SKU:ES8644

Cystatin A Rabbit Polyclonal Antibody

Cystatin A Rabbit Polyclonal Antibody

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Cystatin A Rabbit Polyclonal Antibody

Overview

Product name: Cystatin A rabbit pAb
Alternative Names: Cystatin-A (Cystatin-AS;Stefin-A)
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 60-98
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 11kD
GeneID(Human): 1475
Human Swiss-Prot No: P01040
Cellular localization: Cytoplasm .
Background: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse;
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