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ELK Biotechnology
SKU:ES8594
DCT Rabbit Polyclonal Antibody
DCT Rabbit Polyclonal Antibody
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$248.00 USD
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DCT Rabbit Polyclonal Antibody
Overview
| Product name: | DCT rabbit pAb |
| Alternative Names: | L-dopachrome tautomerase (DCT) (DT) (EC 5.3.3.12) (L-dopachrome Delta-isomerase) (Tyrosinase-related protein 2) (TRP-2) (TRP2) |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen: | Synthetic peptide from human protein at AA range: 171-244 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 59kD |
| GeneID(Human): | 1638 |
| Human Swiss-Prot No: | P40126 |
| Cellular localization: | Melanosome membrane ; Single-pass type I membrane protein . Melanosome . Proper trafficking to melanosome is regulated by SGSM2, ANKRD27, RAB9A, RAB32 and RAB38. . |
| Background: | catalytic activity:L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.,cofactor:Binds 2 zinc ions per subunit.,function:Involved in regulating eumelanin and phaeomelanin levels.,pathway:Pigment biosynthesis; melanin biosynthesis.,similarity:Belongs to the tyrosinase family.,subunit:Tyrosinase, TYRP1 and TYRP2 may form a multienzyme complex., |
| Species Reactivity: | Human;Mouse;(93%) |
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