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ELK Biotechnology

ES8545

MYOZ2 Rabbit Polyclonal Antibody

MYOZ2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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MYOZ2 Rabbit Polyclonal Antibody

Overview

Product name: MYOZ2 rabbit pAb
Alternative Names: MYOZ2 C4orf5
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human MYOZ2. AA range:21-70
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 30kD
GeneID（Human）: 51778
Human Swiss-Prot No: Q9NPC6
Cellular localization: Cytoplasm, myofibril, sarcomere, Z line . Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle. .
Background: The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011],
Species Reactivity: Human;Mouse;Rat
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