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ELK Biotechnology

ES8533

MIB1 Rabbit Polyclonal Antibody

MIB1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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MIB1 Rabbit Polyclonal Antibody

Overview

Product name: MIB1 rabbit pAb
Alternative Names: MIB1 DIP1 KIAA1323 ZZANK2
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 901-950
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 130kD
GeneID（Human）: 57534
Human Swiss-Prot No: Q86YT6
Cellular localization: Cytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite . Cell membrane . Localizes to the plasma membrane (By similarity). According to PubMed:15048887, it is mitochondrial, however such localization remains unclear. Displaced from centriolar satellites in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock. .
Background: This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1). [provided by RefSeq, Jun 2013],
Species Reactivity: Human;Mouse;Rat
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