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ELK Biotechnology

ES8532

RCC1 Rabbit Polyclonal Antibody

RCC1 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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RCC1 Rabbit Polyclonal Antibody

Overview

Product name: RCC1 rabbit pAb
Alternative Names: RCC1 CHC1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: WB 1:500-2000,IHC-p 1:50-200 ELISA 1:10000-20000
Immunogen: Synthetic peptide from human protein at AA range: 301-350
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 45kD
GeneID（Human）: 1104
Human Swiss-Prot No: P18754
Cellular localization: Nucleus . Chromosome . Cytoplasm . Predominantly nuclear in interphase cells (PubMed:12194828). Binds to mitotic chromosomes (PubMed:12194828, PubMed:17435751, PubMed:20668449). .
Background: disease:Patients with Raynaud disease produce antibodies that bind to RCC1.,function:Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1/Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA.,similarity:Contains 7 RCC1 repeats.,subcellular location:Becomes dispersed throughout the cytoplasm during mitosis.,
Species Reactivity: Human;Mouse;Rat
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