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ELK Biotechnology
SKU:ES8481
Beclin-1 Rabbit Polyclonal Antibody
Beclin-1 Rabbit Polyclonal Antibody
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Beclin-1 Rabbit Polyclonal Antibody
Overview
| Product name: | Beclin-1 rabbit pAb |
| Alternative Names: | beclin 1, autophagy related |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen: | Synthesized peptide derived from Beclin-1 . at AA range: 110-190 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 55kD |
| GeneID（Human）: | 8678 |
| Human Swiss-Prot No: | Q14457 |
| Cellular localization: | Cytoplasm . Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein . Endoplasmic reticulum membrane ; Peripheral membrane protein . Mitochondrion membrane ; Peripheral membrane protein . Endosome . Cytoplasmic vesicle, autophagosome . Interaction with ATG14 promotes translocation to autophagosomes. Expressed in dendrites and cell bodies of cerebellar Purkinje cells (By similarity). .; [Beclin-1-C 35 kDa]: Mitochondrion . Nucleus . Cytoplasm .; [Beclin-1-C 37 kDa]: Mitochondrion . |
| Background: | beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015], |
| Species Reactivity: | Human;Mouse;Chicken |
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