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ELK Biotechnology

ES8475

RHEB Rabbit Polyclonal Antibody

RHEB Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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RHEB Rabbit Polyclonal Antibody

Overview

Product name: RHEB rabbit pAb
Alternative Names: Ras homolog enriched in brain
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthetic Peptide of RHEB
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 20kD
GeneID（Human）: 6009
Human Swiss-Prot No: Q15382
Cellular localization: Endomembrane system ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasm, cytosol . Endoplasmic reticulum membrane ; Lipid-anchor ; Cytoplasmic side .
Background: This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat;Predicted:Cow
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