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ELK Biotechnology

SKU:ES8458

MER/TYRO3 (Phospho-Tyr753/Tyr685) Rabbit Polyclonal Antibody

MER/TYRO3 (Phospho-Tyr753/Tyr685) Rabbit Polyclonal Antibody

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MER/TYRO3 (Phospho-Tyr753/Tyr685) Rabbit Polyclonal Antibody

Overview

Product name: MER/TYRO3 (Phospho-Tyr753/Tyr685) rabbit pAb
Alternative Names: MERTK MER
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human MER/TYRO3 (Phospho-Tyr753/Tyr685)
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 110kD
GeneID(Human): 10461/7301
Human Swiss-Prot No: Q12866/Q06418
Cellular localization: Cell membrane ; Single-pass type I membrane protein .
Background: This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008],
Species Reactivity: Human:Y753/Y685;Mouse:Y748/Y675;Rat:Y748/Y675
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