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ELK Biotechnology
SKU:ES8458
MER/TYRO3 (Phospho-Tyr753/Tyr685) Rabbit Polyclonal Antibody
MER/TYRO3 (Phospho-Tyr753/Tyr685) Rabbit Polyclonal Antibody
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MER/TYRO3 (Phospho-Tyr753/Tyr685) Rabbit Polyclonal Antibody
Overview
| Product name: | MER/TYRO3 (Phospho-Tyr753/Tyr685) rabbit pAb |
| Alternative Names: | MERTK MER |
| Applications: | WB;ELISA;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: | Synthesized phospho-peptide around the phosphorylation site of human MER/TYRO3 (Phospho-Tyr753/Tyr685) |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 110kD |
| GeneID(Human): | 10461/7301 |
| Human Swiss-Prot No: | Q12866/Q06418 |
| Cellular localization: | Cell membrane ; Single-pass type I membrane protein . |
| Background: | This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP). [provided by RefSeq, Jul 2008], |
| Species Reactivity: | Human:Y753/Y685;Mouse:Y748/Y675;Rat:Y748/Y675 |
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Western Blot analysis of 293T cells using Antibody diluted at 500. Secondary antibody(catalog#:RS0002) was diluted at 1:20000 -
Immunohistochemical analysis of paraffin-embedded human lung cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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