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ELK Biotechnology

SKU:ES8447

E2F-3 (Acetyl-Lys168) Rabbit Polyclonal Antibody

E2F-3 (Acetyl-Lys168) Rabbit Polyclonal Antibody

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E2F-3 (Acetyl-Lys168) Rabbit Polyclonal Antibody

Overview

Product name: E2F-3 (Acetyl Lys168) rabbit pAb
Alternative Names: E2F3 KIAA0075
Applications: WB;ELISA
Recommended Dilutions: WB: 1:500-10000 ELISA: 1:10000
Immunogen: Synthesized acetyl-peptide from human protein at AA range: 130-200
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 50kD
GeneID(Human): 1871
Human Swiss-Prot No: O00716
Cellular localization: Nucleus.
Background: This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013],
Species Reactivity: Human:K168;Mouse:K160;Rat:K161
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