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ELK Biotechnology
SKU:ES8445
Acetyl-EPAS-1 (K385) Rabbit Polyclonal Antibody
Acetyl-EPAS-1 (K385) Rabbit Polyclonal Antibody
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Acetyl-EPAS-1 (K385) Rabbit Polyclonal Antibody
Overview
| Product name: | Acetyl-EPAS-1 (K385) rabbit pAb |
| Alternative Names: | endothelial PAS domain protein 1 |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000, ELISA 1:10000-20000 |
| Immunogen: | Synthesized acetyl-peptide of Acetyl-EPAS-1 (K385) |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 120kD |
| GeneID(Human): | 2034 |
| Human Swiss-Prot No: | Q99814 |
| Cellular localization: | Nucleus . Nucleus speckle . Colocalizes with HIF3A in the nucleus and speckles. . |
| Background: | endothelial PAS domain protein 1(EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009], |
| Species Reactivity: | Human;Mouse;Rat |
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