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ELK Biotechnology

ES8441

K-Ras Rabbit Polyclonal Antibody

K-Ras Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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K-Ras Rabbit Polyclonal Antibody

Overview

Product name: K-Ras rabbit pAb
Alternative Names: GTPase KRas (K-Ras 2;Ki-Ras;c-K-ras;c-Ki-ras) [Cleaved into: GTPase KRas, N-terminally processed]
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human KRAS. AA range:150-189
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 22kD
GeneID（Human）: 3845
Human Swiss-Prot No: P01116
Cellular localization: Cell membrane ; Lipid-anchor ; Cytoplasmic side . Endomembrane system . Cytoplasm, cytosol .; [Isoform 2B]: Cell membrane ; Lipid-anchor .
Background: This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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