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ELK Biotechnology

ES8439

Synapsin-1 (phospho Ser553) Rabbit Polyclonal Antibody

Synapsin-1 (phospho Ser553) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Synapsin-1 (phospho Ser553) Rabbit Polyclonal Antibody

Overview

Product name: Synapsin-1 (phospho Ser553) rabbit pAb
Alternative Names: SYN1; Synapsin-1; Brain protein 4.1; Synapsin I
Applications: WB;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300
Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Synapsin-1 (phospho Ser553)
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 75kD
GeneID（Human）: 6853
Human Swiss-Prot No: P17600
Cellular localization: Cell junction, synapse. Golgi apparatus .
Background: This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat
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