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ELK Biotechnology

ES8367

Dectin-2 Rabbit Polyclonal Antibody

Dectin-2 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Dectin-2 Rabbit Polyclonal Antibody

Overview

Product name: Dectin-2 rabbit pAb
Alternative Names: CLEC6A; CLECSF10; DECTIN2; C-type lectin domain family 6 member A; C-type lectin superfamily member 10; Dendritic cell-associated C-type lectin 2; DC-associated C-type lectin 2; Dectin-2
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: Synthesized peptide derived from the Internal region of human Dectin-2.
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 23kD
GeneID（Human）: 93978
Human Swiss-Prot No: Q6EIG7
Cellular localization: Cell membrane ; Single-pass type II membrane protein .
Background: The protein encoded by this gene is a type II membrane receptor with an extracellular C-type lectin-like domain fold. The extracellular portion binds structures with a high mannose content and has been shown to recognize several pathogens, including C. elegans, S. cerevisiae, M. tuberculosis, C. neoformans, and house dust mite. When stimulated, the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway, leading to the induction of cytokines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
Species Reactivity: Human;Rat;Mouse;
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