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ELK Biotechnology

SKU:ES8133

Cdc25A Rabbit Polyclonal Antibody

Cdc25A Rabbit Polyclonal Antibody

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Cdc25A Rabbit Polyclonal Antibody

Overview

Product name: Cdc25A rabbit pAb
Alternative Names: CDC25A; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CDC25A. AA range:43-92
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID(Human): 993
Human Swiss-Prot No: P30304
Cellular localization: intracellular,nucleus,nucleoplasm,cytoplasm,cytosol,
Background: cell division cycle 25A(CDC25A) Homo sapiens CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Mouse;Rat;Monkey
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