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ELK Biotechnology

ES8124

Cdc6 Rabbit Polyclonal Antibody

Cdc6 Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Cdc6 Rabbit Polyclonal Antibody

Overview

Product name: Cdc6 rabbit pAb
Alternative Names: CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human CDC6. AA range:491-540
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 60kD
GeneID（Human）: 990
Human Swiss-Prot No: Q99741
Cellular localization: Nucleus . Cytoplasm . The protein is nuclear in G1 and cytoplasmic in S-phase cells (PubMed:9566895). .
Background: The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Cdc6, a protein essential for the initiation of DNA replication. This protein functions as a regulator at the early steps of DNA replication. It localizes in cell nucleus during cell cyle G1, but translocates to the cytoplasm at the start of S phase. The subcellular translocation of this protein during cell cyle is regulated through its phosphorylation by Cdks. Transcription of this protein was reported to be regulated in response to mitogenic signals through transcriptional control mechanism involving E2F proteins. [provided by RefSeq, Jul 2008],
Species Reactivity: Human;Rat;Mouse;
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