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ELK Biotechnology

ES8107

Gab 2 (phospho Ser159) Rabbit Polyclonal Antibody

Gab 2 (phospho Ser159) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Gab 2 (phospho Ser159) Rabbit Polyclonal Antibody

Overview

Product name: Gab 2 (phospho Ser159) rabbit pAb
Alternative Names: GAB2; KIAA0571; GRB2-associated-binding protein 2; GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp100
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human GRB2 around the phosphorylation site of Ser159. AA range:125-174
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 100kD
GeneID（Human）: 9846
Human Swiss-Prot No: Q9UQC2
Cellular localization: Cytoplasm . Cell membrane .
Background: GRB2 associated binding protein 2(GAB2) Homo sapiens This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2009],
Species Reactivity: Human;Mouse;Rat
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