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ELK Biotechnology

SKU:ES8074

N-CoR Rabbit Polyclonal Antibody

N-CoR Rabbit Polyclonal Antibody

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N-CoR Rabbit Polyclonal Antibody

Overview

Product name: N-CoR rabbit pAb
Alternative Names: NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human NCoR1. AA range:51-100
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 270kD
GeneID(Human): 9611
Human Swiss-Prot No: O75376
Cellular localization: Nucleus .
Background: This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010],
Species Reactivity: Human;Mouse
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