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ELK Biotechnology

ES8062

p130 Cas (phospho Tyr249) Rabbit Polyclonal Antibody

p130 Cas (phospho Tyr249) Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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p130 Cas (phospho Tyr249) Rabbit Polyclonal Antibody

Overview

Product name: p130 Cas (phospho Tyr249) rabbit pAb
Alternative Names: BCAR1; CAS; CASS1; CRKAS; Breast cancer anti-estrogen resistance protein 1; CRK-associated substrate; Cas scaffolding protein family member 1; p130cas
Applications: WB;IHC;IF;ELISA
Recommended Dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human p130 Cas around the phosphorylation site of Tyr249. AA range:215-264
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 130kD
GeneID（Human）: 9564
Human Swiss-Prot No: P56945
Cellular localization: Cell junction, focal adhesion . Cytoplasm . Cell projection, axon . Unphosphorylated form localizes in the cytoplasm (By similarity). Localizes to focal adhesion sites following integrin engagement (By similarity). .
Background: BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]).[supplied by OMIM, May 2009],
Species Reactivity: Human;Mouse;Rat
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