Skip to product information
1 of 1

ELK Biotechnology

SKU:ES8047

PERK Rabbit Polyclonal Antibody

PERK Rabbit Polyclonal Antibody

Regular price $248.00 USD
Regular price Sale price $248.00 USD
Sale Sold out
Shipping calculated at checkout.
Size

PERK Rabbit Polyclonal Antibody

Overview

Product name: PERK rabbit pAb
Alternative Names: EIF2AK3; PEK; PERK; Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK
Applications: IF;WB;IHC;ELISA
Recommended Dilutions: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Immunogen: The antiserum was produced against synthesized peptide derived from human EIF2AK3. AA range:947-996
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 125kD
GeneID(Human): 9451
Human Swiss-Prot No: Q9NZJ5
Cellular localization: Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Background: The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015],
Species Reactivity: Human;Mouse;Rat
View full details