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ELK Biotechnology

ES8028

Neurexin IIIβ Rabbit Polyclonal Antibody

Neurexin IIIβ Rabbit Polyclonal Antibody

$248.00 USD
$248.00 USD
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Neurexin IIIβ Rabbit Polyclonal Antibody

Overview

Product name: Neurexin IIIβ rabbit pAb
Alternative Names: NRXN3; KIAA0743; Neurexin-3-beta; Neurexin III-beta
Applications: WB;ELISA;IHC
Recommended Dilutions: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
Immunogen: Synthesized peptide derived from Neurexin IIIβ . at AA range: 30-110
Storage: Rabbit
Storage: -20°C/1 year
Clonality: Polyclonal
Isotype: IgG
Concentration: 1 mg/ml
Observed Band: 70kD
GeneID（Human）: 9369
Human Swiss-Prot No: Q9HDB5
Cellular localization: Membrane ; Single-pass type I membrane protein .
Background: NRXN3 (neurexin 3) encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder.
Species Reactivity: Human;Rat;Mouse;
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